Sildenafil (generic of Viagra) is a drug used to treat erectile dysfunction in adult men. It belongs to the group of phosphodiesterase 5 inhibitor drugs (such as Levitra, Cialis, Tadalafil), and is the same active ingredient as Viagra. It takes approximately one hour before sexual activity, and lasts approximately 4 hours. Before you know if you can take it, its mechanism of action, recommended dose, duration of action, contraindications, adverse effects, interactions with other drugs, ways to buy it, price and presentations available, find out everything you need to know below.
About Sildenafil: Sildenafil is a drug used to treat erectile dysfunction, generic version of Viagra.
What is it?
Cheap sildenafil is an inhibitor of phosphodiesterase 5, whose active ingredient is the same as the drug Viagra. It is used for male sexual performance disorders, especially erectile dysfunction.
Lab: Initially, only Pfizer was licensed to sell the active ingredient Sildenafil under the trade name Viagra worldwide. But today, many laboratories are authorized to market cheap Sildenafil. Some of them are: Actavis, Alter, Apotex, Aristo, Aurovit, Aurovitas, Cinfa, Cinfamed, Combix, Dr.Reddys, Farmalider, Kern Pharma, Krka, Macleods, Mylan, Normon, Pensa, Qualigen, Ratiopharm, Sandoz, Stada, Stadagen, Tarbis, Tecnigen, Teva, Tevagen.
Form of administration: The intake of Sildenafil is one tablet orally, with a glass of water, 30 to 60 minutes before initiating sexual activity.
Presentations available: Sildenafil comes in film-coated tablets of 25 mg, 50 mg and 100 mg; as well as chewable tablets of 25 mg, 50 mg and 100 mg.
Price per tablet: The price per tablet to buy cheap Sildenafil may vary depending on the concentration and amount of tablets in the box.
Price of Sildenafil 25 mg: prices ranging from € 0.28 to € 1.00 per tablet, in boxes containing 30 to 180 tablets.
Price of Sildenafil 50 mg: prices ranging from € 0.57 to € 2.51 per tablet, in boxes containing from 10 to 180 tablets.
Sildenafil 100 mg price: prices ranging from € 0.76 to € 2.79 per tablet, in boxes containing 10 to 180 tablets.
Start of action: its start of action is 30 to 60 minutes after taking the tablet, so on average it is recommended to take it approximately one hour before the sexual encounter.
Duration of action: Its effect lasts in the body from four to five hours on average.
Interaction with food: it is recommended to take it on an empty stomach, as abundant meals may delay its absorption and interfere with its action.
Side effects: Some adverse reactions that may occur with the intake of Sildenafil may be: headache, dizziness, abdominal pain, vomiting, muscle aches, facial swelling, chills, tachycardia, anemia, insomnia, difficulty breathing, among others.
How does Sildenafil work?
Sildenafil is a phosphodiesterase 5 inhibitor. It achieves a satisfactory erection through a complex mechanism in which the ultimate goal is to have more vasodilation of the corpora cavernosa of the penis with greater blood flow; this is achieved through the inhibition of phosphodiesterase 5, an enzyme that degrades the most important mediator of penis blood vessel dilation and thus increases nitric oxide so important for male erection.
Why switch to Tadalafil?
Sildenafil is the generic version of Viagra, with the same active ingredient so effectively used for years by thousands of men around the world. The advantage of generic products is that they have the same effects of renowned brand names (such as Viagra), as well as their advantages, for a much lower price.
Instructions for use and dosage of the drug Sildenafil
Sildenafil is taken orally 30 to 60 minutes before planned sexual activity, an average of one hour before, with a glass of water.
The initial recommended dose is 50 mg (average presentation), which can be reduced to 25 mg or increased to 100 mg, depending on efficacy and patient tolerability.
The maximum recommended dose is one tablet of its maximum presentation, once a day.
Is Sildenafil effective every time?
Sildenafil has high rates of successful post-take penetration, with more than 70% of users satisfied. Although the response of each organism depends on multiple factors that can vary, sildenafil has proven to be quite effective.
Possible undesirable effects of the drug Sildenafil
Some adverse effects that have been reported with Sildenafil can be organized by systems:
- General: face swelling, cellulite, allergic reactions, weakness, generalized pain, chills, headache.
- Cardiovascular: angina, migraines, fainting, tachycardia, palpitations, hypotension, myocardial infarction, stroke, cardiac arrest, abnormal electrocardiogram.
- Digestive: nausea, vomiting, abdominal pain and inflammation, gastritis, gastroenteritis.
- In blood: anemia, leukopenia.
- Metabolism: generalized swelling, thirst, increase or decrease in glycemia.
- From limbs: inflammation and pain of joints, muscular pains, bone pain.
- Nervous system: tingling, tremor, vertigo, dizziness, depression, insomnia, drowsiness, nightmares.
- Respiratory: asthma, shortness of breath, laryngitis, bronchitis.
- Skin: hives or general allergic reaction, itching, sweating, contact dermatitis.
- Sense organs: conjunctivitis, sensitivity to light, eye pain, deafness, ear pain, eye bleeding, dry eyes, blurred vision.
- Urogenital: increased urinary frequency, abnormal ejaculation, genital swelling.
Contraindications: cases in which Sildenafil should not be taken
- Hypersensitivity to Sildenafil or any of the other components of the formula.
- Women, and children under the age of 18.
- Patients who are taking nitric oxide (nitrates and nitrites), as Sildenafil can potentiate its hypotensive effects.
- History of hereditary disorders of the retina, such as retinitis pigmentosa.
- Hypotension (blood pressure less than 90/50 mmHg).
- Severe cardiovascular dysfunctions, unstable angina and severe heart failure.
- Recent history of myocardial infarction or stroke.
- Severe liver failure.
- Combination with CYP3A4 inhibitors (ketoconazole, itraconazole, ritonavir).
- Patients with a history of vision loss from non-arteritic anterior ischemic optic neuropathy regardless of whether or not this episode was associated with prior exposure to a phosphodiesterase 5 inhibitor.
- Concomitant use with other phosphodiesterase 5 inhibitors, or any other treatment to treat erectile dysfunction.
Interactions of the drug Sildenafil with other substances
There are certain medications that can decrease or increase the clearance of Sildenafil, or with which it can suffer alterations in your metabolism, such as: isoenzyme inhibitors cytochrome P450; cimetidine; erythromycin; ketoconazole, itraconazole, mibefradil; CYP3A4 inducers, such as rifampicin; amlodipine; organic nitrates.
Fertility, Pregnancy, and Breastfeeding
No alterations of fertility have been evidenced with the taking of Sildenafil. Mobility and sperm count were shown to be normal with intake of Sildenafil in healthy men.
Sildenafil is not indicated in women or children, so its intake in pregnancy or lactation is contraindicated.
FAQ (Frequently Asked Questions):
Why should patients consult a doctor before taking erectile dysfunction treatment for the first time?
All medications have specific therapeutic indications, contraindications, risks, adverse effects and details that are only well known to the physician with mastery of the patient’s medical history. In addition to those used to treat erectile dysfunction, the dosage to start the treatment is individualized depending on each particular case, so it is ideal to consult the family doctor before starting taking it.
What is the difference between Sildenafil and Viagra?
Sildenafil is the generic version of Viagra, but the active ingredient, dosage and other characteristics of the product are shared. The only difference is that Sildenafil, being a generic product, is cheaper than the brand name Viagra.
Is Sildenafil stronger than Viagra?
The active ingredient Sildenafil is shared by Viagra, so it cannot be said that one is stronger than the other.
What is the recommended dosage to start taking Sildenafil?
The initial dose recommended to start treatment for erectile dysfunction with Sildenafil is its presentation of 50 mg (its average presentation), which may be decreased to its dose of 25 mg or increased to 100 mg, depending on its effectiveness and the tolerability of the patient.
Is there a generic?
Sildenafil is the generic version of Viagra.
Why does the price vary so much?
Laboratories sell to pharmacies at an established price that is the same for all transactions, but once this happens, pharmacies are free to set the price at which they will sell it to the general public. In addition, with the modality of buying cheap Sildenafil at a pharmacy or buying Sildenafil online without a prescription, the cost may vary depending on the many factors that influence the different options.
How long do the effects of Sildenafil last, and how often can I take it?
The effects of Sildenafil on the body last approximately 4 to 5 hours, and the maximum recommended dose is one tablet per day.
Can I drink alcohol if I am taking sildenafil?
Alcohol in small amounts does not seem to interfere with the absorption of Sildenafil, but consumed in copious or abundant amounts can interfere with the ability to get an erection.
It is important to note that alcohol alone can affect male erectile function.
Can I take Sildenafil while taking other medications?
Sildenafil has several interactions with other substances, so it is ideal to consult a doctor before starting its intake so that it, based on medical history and history, decides whether it is appropriate for the patient.
Can Sildenafil cause unwanted erections?
To get an erection with the intake of Sildenafil, prior sexual stimulation is necessary, so it is not usual to cause spontaneous unwanted erections. Cases of priapism (painful erection for more than four hours) by ingestion of Sildenafil, are quite rare.
Can I split Sildenafil so as not to take the whole tablet?
It is not recommended to split any tablet in half, as the resulting dose may be inaccurate. However, if it is ever necessary to do so, the doctor may consider and explain the correct way to divide the dose to avoid complications.
Do I need a prescription to buy Sildenafil or can I buy it without one?
Medications for erectile dysfunction usually merit a doctor’s prescription to be purchased, but with the new modalities it is now possible to buy Sildenafil without a prescription, especially when buying cheap Sildenafil online.
Is sildenafil less expensive online than in a pharmacy?
Depending on various factors such as shipping costs, medical consultation and others, the prices of cheap Sildenafil are variable. Sometimes, for example because you don’t have to go to the office and pay for the doctor’s office, buying Sildenafil online can be cheaper than buying Sildenafil at its pharmacy price.
What should I do if Sildenafil does not work or if Sildenafil becomes ineffective over time?
If Sildenafil does not have the desired effect, or simply stops working after some time of consumption, it is ideal to consult a doctor to adjust the dose. Most likely the doctor will try to increase to maximum doses to see if this makes any changes effective, and if this does not work, perform tests to verify what is happening or if you need to change drugs.
Never try to take more Sildenafil than the maximum per day, or take another phosphodiesterase 5 inhibitor at the same time, or any medication for erectile dysfunction. This will not enhance the effect, and can lead to serious adverse reactions.